KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIBCH
All Species:
32.42
Human Site:
T321
Identified Species:
50.95
UniProt:
Q6NVY1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVY1
NP_055177.2
386
43482
T321
L
M
E
G
S
S
K
T
L
Q
E
V
L
T
M
Chimpanzee
Pan troglodytes
XP_515988
440
48807
T375
L
M
E
G
S
S
K
T
L
Q
E
V
L
T
M
Rhesus Macaque
Macaca mulatta
XP_001103467
444
49874
T379
L
M
E
G
S
S
K
T
L
Q
E
V
L
T
M
Dog
Lupus familis
XP_848689
359
39946
Y303
Q
E
V
L
T
M
E
Y
R
L
S
Q
A
C
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS1
385
43019
T320
L
M
E
G
S
S
K
T
L
Q
E
V
L
I
M
Rat
Rattus norvegicus
Q5XIE6
385
43006
T320
L
M
E
G
S
T
K
T
L
Q
E
V
L
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ60
385
42810
S320
L
R
E
G
A
T
M
S
L
Q
D
V
F
T
M
Frog
Xenopus laevis
A2VDC2
385
42348
S320
L
K
E
G
A
S
M
S
L
Q
E
V
L
T
M
Zebra Danio
Brachydanio rerio
Q58EB4
382
42258
S317
I
E
E
G
A
R
M
S
L
Q
E
V
F
M
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650453
385
42729
I325
L
S
L
A
Q
C
L
I
M
E
Y
R
L
A
V
Honey Bee
Apis mellifera
XP_396249
396
44074
K326
L
N
L
A
D
C
L
K
M
E
F
R
L
M
C
Nematode Worm
Caenorhab. elegans
P34559
288
31153
P232
E
K
I
A
D
Q
S
P
L
I
V
Q
M
A
K
Sea Urchin
Strong. purpuratus
XP_791196
379
41899
T314
L
I
E
G
A
K
L
T
L
G
N
C
L
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PEY5
378
42237
G318
I
S
K
D
F
V
E
G
C
R
A
V
L
I
D
Baker's Yeast
Sacchar. cerevisiae
P28817
500
56270
L324
A
Q
E
I
K
T
K
L
L
T
K
S
P
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.9
84.4
N.A.
81.8
81.6
N.A.
N.A.
69.1
69.6
65.2
N.A.
49.2
47.9
24.6
56.9
Protein Similarity:
100
86.8
86.2
87.8
N.A.
92.2
92.2
N.A.
N.A.
83.9
81.3
78.2
N.A.
67.6
67.1
40.9
75.1
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
N.A.
53.3
73.3
46.6
N.A.
13.3
13.3
6.6
46.6
P-Site Similarity:
100
100
100
20
N.A.
93.3
100
N.A.
N.A.
80
86.6
66.6
N.A.
33.3
26.6
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.8
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
20
27
0
0
0
0
0
7
0
7
14
0
% A
% Cys:
0
0
0
0
0
14
0
0
7
0
0
7
0
7
7
% C
% Asp:
0
0
0
7
14
0
0
0
0
0
7
0
0
0
7
% D
% Glu:
7
14
67
0
0
0
14
0
0
14
47
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
7
0
14
0
0
% F
% Gly:
0
0
0
60
0
0
0
7
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
7
7
7
0
0
0
7
0
7
0
0
0
14
0
% I
% Lys:
0
14
7
0
7
7
40
7
0
0
7
0
0
0
7
% K
% Leu:
67
0
14
7
0
0
20
7
74
7
0
0
67
0
0
% L
% Met:
0
34
0
0
0
7
20
0
14
0
0
0
7
14
60
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% P
% Gln:
7
7
0
0
7
7
0
0
0
54
0
14
0
0
0
% Q
% Arg:
0
7
0
0
0
7
0
0
7
7
0
14
0
0
0
% R
% Ser:
0
14
0
0
34
34
7
20
0
0
7
7
0
14
7
% S
% Thr:
0
0
0
0
7
20
0
40
0
7
0
0
0
40
0
% T
% Val:
0
0
7
0
0
7
0
0
0
0
7
60
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _